Before You Arrive
Ayahuasca Ceremony Preparation & Integration
Preparing thoughtfully is an essential part of the ceremonial experience. Please read this page carefully before attending.
Important — health & medication safety
Read Before Registering
Ayahuasca/Daime contains compounds with MAOI activity. Medication, supplement, substance, and health interactions can be serious or life-threatening. You must disclose every prescription medicine, over-the-counter medicine, supplement, and substance you use on the medical form and contact the facilitator before attending.
Do not stop, start, or change prescribed medication on your own. Only your licensed prescriber can advise on a safe medication plan or washout period.
Read our confidential screening process →Diet & Physical Preparation
Preparation is part of the ceremony. Follow a simple, fresh-food diet and avoid alcohol, recreational drugs, processed foods, excess sugar, and heavy or spicy meals in the days leading up to the retreat. Choose light, nourishing foods that support hydration, digestion, and rest.
Foods high in tyramine or that are aged, cured, fermented, overripe, or poorly stored can interact with MAOI-active substances and may cause severe symptoms. Follow the food restrictions below exactly and ask before the retreat if you are uncertain about any food, supplement, or preparation practice.
Foods to Avoid
Avoid the following for at least 72 hours before and after the ceremony:
- –Red meat that is not fresh, especially unfresh liver
- –Smoked, fermented, aged or dried fish, lox; any fish that is not fresh
- –Sausage, bologna, pepperoni, salami, corned beef
- –Aged cheeses (cottage cheese and cream cheese are safe)
- –Protein extracts; liquid and powdered protein dietary supplements
- –Brewer's yeast, yeast vitamin supplements, or yeast extracts
- –Fermented tofu, fermented bean curd, fermented soybean paste, soy sauce
- –Canned soups or soups made with protein extracts or bouillon
- –Miso soup (contains fermented bean curd)
- –Shrimp paste; sauerkraut
- –Bruised or slightly overripe fruits, especially bananas and apples; raisins and other dried fruits
- –Avocados, if ripe or overripe
- –Alcohol in all forms — recommended to avoid for at least one week prior
- –Dairy products close to expiration or unrefrigerated (fresh yogurt is safe)
- –Excessive salt, pepper, garlic, oils, butter, and other animal fats
- –Aspartame and refined sugar in all forms
- –Fava beans (especially if overripe), peanuts, raspberries, spinach, chocolate — in large quantities
- –Caffeine in large quantities
Medications & Recreational Drugs to Avoid Before the Ceremony
Do not combine Daime/Ayahuasca with recreational or synthetic drugs, alcohol, cannabis, mushrooms, or any medication or supplement that has not been individually reviewed. Never use this page to determine a washout period or to stop a prescribed medicine.
A note about timing and medication changes
Daime/Ayahuasca contains compounds with MAOI activity. Interactions with certain medicines, over-the-counter products, supplements, herbs, and recreational drugs may be severe or life-threatening. Two weeks is a common minimum mentioned for some prescription MAOI interactions, but it is not a universal washout period. Depending on the medicine, dose, duration of use, and your health history, a clinician may recommend a different plan or determine that participation is not appropriate.
Do not stop, taper, or change any prescribed medication for a ceremony. Speak with the clinician who prescribes it and disclose every medicine, supplement, and substance on your medical form before you travel or register.
Serotonergic medicines and serotonin syndrome
Medicines that affect serotonin — including SSRIs, SNRIs, tricyclic antidepressants, MAOIs, certain migraine medicines, stimulants, cough medicines containing dextromethorphan, lithium, tramadol, and some supplements such as 5-HTP or St. John's Wort — require individual review. Combining serotonergic medicines with MAOI activity can increase the risk of serotonin syndrome, a potentially life-threatening drug reaction.
Longer washout examples are medicine-specific
Fluoxetine (Prozac) is an important example: official prescribing information uses a five-week interval before starting a prescription MAOI in many circumstances because fluoxetine can remain in the body for a long time. This is an example of why a general two-week rule cannot be used for every medicine; only the prescribing clinician can determine an appropriate plan for an individual.
Opioids, alcohol, sedatives, and anesthetics
Opioids (including codeine, morphine, heroin, oxycodone, buprenorphine, tramadol, and related medicines), alcohol, sleeping pills, tranquilizers, and anesthetics can affect breathing, consciousness, and sedation. They must be disclosed and reviewed before participation. Alcohol and recreational drugs are not permitted before or during ceremony.
Blood-pressure, heart, respiratory, and herbal products
Diuretics, vasodilators, stimulants, decongestants, heart or blood-pressure medicines, asthma or breathing medicines, and products that affect the nervous system can alter blood pressure, heart rate, or alertness. Nutmeg at psychoactive doses and cowhage (Mucuna pruriens) are also not pre-approved. Review these products with a licensed prescriber or pharmacist before attending.
High-risk interaction categories include:
- –Antidepressants and other serotonergic medicines, including SSRIs, SNRIs, tricyclic antidepressants, and MAOIs
- –Prescription and non-prescription stimulants, decongestants, and ADHD medicines
- –Opioids and opioid-containing pain medicines
- –Sleep medicines, tranquilizers, anesthetics, and medicines that can cause sedation
- –Blood-pressure, heart-rhythm, respiratory, neurological, and Parkinson’s medicines
- –Herbal products and supplements that can affect serotonin, blood pressure, or the nervous system
Strictly Prohibited:
- ✕All recreational or synthetic drugs (cocaine, MDMA, LSD, amphetamines, heroin)
- ✕Alcohol
- ✕Cannabis in any form
- ✕Other psychedelics, including mushrooms
Medication and supplement review list (A–Z)
This is a screening list of medicines and substances that require disclosure and an individual review by your prescribing clinician, pharmacist, and the facilitation team before participation. It is not a complete interaction checker: a medicine appearing here is not automatically suitable or unsuitable, and an unlisted medicine is not automatically safe.
Actifed
Adderall
Alaproclate
Albuterol (Proventil, Ventolin)
Amantadine hydrochloride (Symmetrel)
Amiflamine
Amineptine
Amitriptyline
Amoxapine (Asendin)
Atomoxetine
Bazinaprine
Befloxetone
Befol
Benadryl
Benmoxinb (Nerusil, Neuralex)
Benylin
Benzedrine
Benzphetamine (Didrex)
Bicifadine
Brasofensine
Brofaromine (Consonar)
Buprenorphine
Bupropion (Wellbutrin)
Buspirone (BuSpar)
Butriptyline
Carbamazepine (Tegretol, Epitol)
Chlorpheniramine
Chlor-Trimeton
Cimoxetone
Citalopram (Celexa)
Clomipramine (Anafranil)
Clorgyline
Codeine
Cyclobenzaprine (Flexeril)
Cyclizine (Marezine)
D-deprenyl
Dapoxetine
Desipramine (Pertofrane, Norpramin)
Desvenlafaxine
Dextroamphetamine (Dexedrine)
Dextromethorphan (DXM)
Dibenzepin
Dienolide kavapyrone desmethoxyyangonin
Diethylpropion
Disopyramide (Norpace)
Disulfiram (Antabuse)
Dobutamine
Dopamine (Intropin)
Dosulepin
Doxepin (Sinequan)
Duloxetine (Cymbalta)
Emsam
Entacapone
Ephedrine
Epinephrine (Adrenalin)
Escitalopram (Lexapro)
Esuprone
Etorphine
Femoxetine
Fenfluramine (Pondimin)
Flavoxate hydrochloride (Urispas)
Fluoxetine (Prozac)
Fluvoxamine
Furazolidone (Furoxone)
Gabapentin
Guanethedine
Guanadrel (Hylorel)
Guanethidine (Ismelin)
Hydralazine (Apresoline)
Hydrazine
5-Hydroxytryptophan (5-HTP)
Imipramine (Tofranil)
Iprindole
Iproniazid (Marsilid, Iprozid, Ipronid, Rivivol, Propilniazida)
Iproclozide (Sursum)
Isocarboxazid (Marplan)
Isoniazid (Laniazid, Nydrazid)
Isoniazid/rifampin (Rifamate, Rimactane)
Isoproterenol (Isuprel)
L-dopa (Sinemet)
Ladostigil
Lazabemide (Pakio, Tempium)
Levodopa (Dopar, Larodopa)
Linezolid (Zyvox, Zyvoxid)
Lithium (Eskalith)
Lofepramine
Loratadine (Claritin)
Maprotiline (Ludiomil)
Mebanazine (Actomol)
Medifoxamine
Melitracen
Meperidine (Demerol)
Metaproterenol (Alupent, Metaprel)
Metaraminol (Aramine)
Metfendrazine (Inkazan)
Methamphetamine (Desoxyn)
Methyldopa (Aldomet)
Methylphenidate (Ritalin)
Metralindole
Mianserin
Milacimide
Milnacipran
Minaprine (Cantor)
Mirtazapine (Remeron)
Mofegeline
Moclobemide (Aurorix, Manerix)
Monomethylhydrazine
Montelukast (Singulair)
Nalbufrine
Naloxone
Naltrexone
Nefazodone
Nialamide (Niamid)
Nisoxetine
Nomifensine
Norepinephrine (Levophed)
Nortriptyline (Aventyl)
Octamoxin (Ximaol, Nimaol)
Oxybutynin chloride (Ditropan)
Oxycodone
Oxymetazoline (Afrin, Dimetapp)
Oxymorphone
Orphenadrine (Norflex)
Pargyline (Eutonyl)
Parnate
Paroxetine (Paxil)
Pemoline (Cylert)
Percocet
Pethidine (Demerol)
Phendimetrazine (Plegiline)
Phenelzine (Nardil, Nardelzine)
Pheniprazine (Catron)
Phenmetrazine
Phenoxypropazine (Drazine)
Phentermine
Phenylephrine (Dimetane, Dristan decongestant, Neo-Synephrine)
Phenylhydrazine
Phenylpropanolamine (in many cold medicines)
Phenergan
Pirlindole (Pirazidol)
Procarbazine (Matulane)
Procainamide (Pronestyl)
Protriptyline (Vivactil)
Pseudoephedrine
Quinidine (Quinidex)
Rasagiline (Azilect)
Reboxetine
Reserpine (Serpasil)
Risperidone
Salbutamol
Salmeterol
Selegiline (Eldepryl, Emsam, Zelapar)
Sercloramine
Sertraline (Zoloft)
Sibutramine
Sumatriptan (Imitrex)
Terfenadine (Seldane-D)
Temaril
Tesofensine
Tetrindole
Theophylline (Theo-Dur)
Thesbutiaint
Thioridazine (Mellaril)
Tianeptine
Tolcapone
Toloxatone (Humoryl)
Tramadol
Tranylcypromine (Parnate)
Trazodone
Tricyclic antidepressants (including Amitriptyline, Elavil)
Trimipramine (Surmontil)
Triptans
Tyrima
Vanoxerine
Venlafaxine (Effexor)
Viloxazine
Yohimbine
Zimelidine
Ziprasidone (Geodon)
Herbs to avoid at least 48 hours before and after:
If you are unsure about a medication, do not assume it is safe. Record it on your medical form and contact the facilitator and your prescriber before arriving.
Important health screening
Conditions Requiring Review
The following conditions may increase risk and require disclosure and individual review before participation. They may make participation unsuitable; the facilitator cannot replace medical or mental-health care.
- !Unstable Diabetes Mellitus
- !Disorders of the kidneys
- !Epilepsy
- !Severe neurological malfunctions
- !Illnesses of the circulation (angina pectoris, CVAs, pheochromocytoma, hyperthyroidism)
- !Disorders of the liver
- !Severe unstable mental health disorders (schizophrenia, psychoses, borderline personality disorders)
If you have a history of substance dependence, are under active medical or dental treatment, or have any other health concern, disclose it before travel so an appropriate plan can be considered.
Eating Prior to the Ceremony
Eat simply on ceremony day: a nourishing breakfast and a light lunch generally provide energy without creating unnecessary discomfort. Then fast or eat very lightly for several hours before drinking the sacrament, following the facilitator's specific timing instructions. Hydrate normally, but do not overconsume water immediately before the ceremony.
Appearance & Clothing
Wear comfortable, modest clothing in white or beige, free of prints or words. Avoid belts or restrictive pieces. Wear layers — body temperature may change during the ceremony.
Mental & Spiritual Preparation
Be mindful of what you take in — what you listen to, what you speak, and what you surround yourself with. Choose information and environments that feel uplifting, grounding, and nourishing. In the few days before ceremony, consider creating more quiet around yourself: reduce unnecessary information, limit social-media use, and make room for rest, reflection, and inner exploration. This gentle simplification can help you arrive feeling more present, centered, and connected to your intention.
- •Sit in silence to clarify your intentions. Meditate, journal, or reflect on what you are calling in.
- •Include movement — simple exercises, stretching, or dance.
- •Spend time in nature whenever possible.
After the Ceremony
Eating helps with grounding. We recommend light foods such as soup and fruit, with plenty of water, continuing the recommended diet for one to two more days.
Ayahuasca may continue working within you for up to three days. Use this time to integrate and reflect on what you've learned. Allow yourself gentleness, rest, and quiet time.
Integration
True change unfolds through integration — weaving the insights and lessons from ceremony into your daily life. This is how we live the medicine, transforming visions into action and wisdom into embodied awareness.
Create Space for Stillness
Give yourself moments of quiet each day — journal, meditate, or sit in nature. Allow the lessons to surface naturally.
Nourish the Body
Eat light, clean, whole foods. Include healthy fats like avocado, coconut, or olive oil. Avoid processed food, sugar, caffeine, alcohol, and heavy meats.
Support with Gentle Supplements
Magnesium, Vitamin C, B-complex, Probiotics, Tulsi, or Reishi. Avoid strong or psychoactive herbs for a few weeks.
Ground and Restore
Walk barefoot on the earth. Take Epsom salt baths. Practice gentle yoga, stretching, or dance.
Emotional & Mental Care
Allow emotions to move freely. Share only with people who understand sacred experiences. Everything that surfaces is part of healing.
Bring Teachings into Daily Life
Ask yourself: What did I learn about love, truth, or myself? How can I live in alignment with that today?
Retreat Schedule
Retreats take place on the Maui, Hawaii. The program typically includes:
- •Preparation practices: breathwork, yoga, grounding exercises, sound bath
- •Ceremonial work in a respectful and supportive environment
- •Time for adventure and connection with nature
- •Group sharing circles
- •Integration guidance following the retreat
Medical Guidance
Participants are asked to carefully review their physical and mental health before attending. This work is not intended to replace professional medical or psychological treatment.
Conditions that carry additional risk:
- –Unstable Diabetes Mellitus
- –Disorders of the kidneys
- –Epilepsy
- –Severe neurological malfunctions
- –Illnesses of the circulation (angina pectoris, CVAs, pheochromocytoma, hyperthyroidism)
- –Disorders of the liver
- –Severe unstable mental health disorders (schizophrenia, psychoses, borderline personality disorders)
Spiritual Use Statement
Colibri Sanctuary offers retreats within a spiritual and contemplative context intended to support personal reflection, ethical development, and the exploration of consciousness. This work is not intended to diagnose, treat, or replace medical or psychological care.
Participation is voluntary and based on personal responsibility. Individuals are encouraged to consider their physical, emotional, and mental readiness before taking part.